The eco-protection acts imply reorganising the manufacture business, towards product-service supply chains. The innovation can be tackled at two ranges: - the presetting of the knowledge management surroundings, to deal with the extended producers’ responsibility; - the incorporation of the entrepreneurial facility/function assembly, to accomplish the product-service delivery. The paper surveys the knowledge management frame, specifying the standard PLM aids, with account of the PLM-SE and PLM-RL requirements, giving especial attention on the alternative net-concern options, from virtual, to extended enterprises infra-structures. For explanatory purposes, the study discusses example extended enterprise deployments, and related knowledge management frames, for SE applications ruled by SME contexts; and examines example virtual enterprise settings, with related information networking requirements, for RL applications, according to the EU enacted rules for the ELV recovery (reuse, recycle) domain. The developments relate the impending changes, needed by the current manufacture business, today, perhaps, too much neglected, by most industrial companies, due to incumbent economical vicissitude. The competition, however, is ceaseless spur, and the axiom innovate or perish should suggest to consider the eco-protection acts, rather than charges, the opportunity to reorganise the manufacture business, with the suited incorporation of intangible value added.